2015 Meeting Presentations-Saturday

MEET THE PROFESSOR BREAKFAST SESSIONS

THANKS BUT NO THANKS: DEALING WITH REFUSAL OF MEDICALLY NECESSARY TREATMENT
Sylviane Forget MD and William Wenner MD

CROHN’S DISEASE: COMPLICATED CASES
Athos Bousvaros MD and Brian P. Regan Sr. DO

MEET THE FDA
Andrew Mulberg MD and Juli Tomaino, MD, Jessica Lee, MD and Kerry Jo Lee, MD

TRANSITION TO TRANSFER OF CARE
Laurie Fishman MD and Nitika Gupta MD

HEPATITIS B
Phil Rosenthal MD and Douglas Mogul MD

MANAGEMENT OF GASTROINTESTINAL AND NUTRITIONAL MANIFESTATIONS OF CYSTIC FIBROSIS
Maria Mascarenhas MBBS and Meghana Sathe, MD

HOW TO ACE THE ACE
Leonel Rodriguez MD, Jason Dranove MD and Sheila Bell

LA B DE HEPATITIS EN NIÑOS (no charge)
Regino Gonzalez Peralta MD and Aymin Delgado-Borrego MD, MP

PLENARY SESSION II

Fellow Research Award
AN INNOVATIVE MUCOSAL IMPEDANCE DEVICE DIFFERENTIATES ACTIVE EOSINOPHILIC ESOPHAGITIS FROM INACTIVE DISEASE, NERD, AND CONTROLS.
Mary Allyson Lowry1, Michael F. Vaezi2, Hernan Correa3, Tina Higginbotham2, James C. Slaughter4, Sari Acra1. 1Pediatric Gastroenterology, Vanderbilt University, Nashville, TN, USA; 2Gastroenterology, Vanderbilt University, Nashville, TN, USA; 3Pediatric Pathology, Vanderbilt University, Nashville, TN, USA; 4Biostatistics, Vanderbilt University, Nashville, TN, USA.

Young Faculty Investigator Award
LOSS OF NUCLEAR RECEPTOR LRH-1 SENSITIZES INTESTINAL EPITHELIUM TO INFLAMMATORY INJURY.
James R. Bayrer1, Robert Fletterick2, Ophir Klein4, Holly Ingraham3. 1Pediatric Gastroenterology, U.C. San Francisco, San Francisco, CA, USA; 2Biochemistry and Biophysics, U.C. San Francisco, San Francisco, CA, USA; 3Cellular and Molecular Pharmacology, U.C. San Francisco, San Francisco, CA, USA; 4Orofacial Sciences and Pediatrics, U.C. San Francisco, San Francisco, CA, USA.

KEYNOTE ADDRESS: 21ST CENTURY HEALTH CARE POLITICS AND THE CHALLENGES THEY POSE TO PEDIATRIC ACADEMIC MEDICINE
Atul Grover MD, Association of American Medical Colleges

Young Faculty Clinical Investigator Award
PANTOPRAZOLE PHARMACOKINETICS IN OBESITY: WHERE GENES AND SIZE COLLIDE.
Valentina Shakhnovich1,2, Susan Abdel-Rahman2, Craig Friesen1, Jaylene Weigel2, Robin E. Pearce2, Andrea Gaedigk2, J Steven Leeder2, Gregory L. Kearns2. 1Gastroenterology, Hepatology and Nutrition, Children's Mercy Hospital, Kansas City, MO, USA; 2Clinical Pharmacology, Toxicology and Therapeutic Innovation, Children's Mercy Hospital, Kansas City, MO, USA.

William Balistreri Prize
SELECTIVE SEROTONIN REUPTAKE INHIBITORS HAVE CRITICAL AND LONG-LASTING EFFECTS ON ENTERIC NERVOUS SYSTEM DEVELOPMENT AND GASTROINTESTINAL FUNCTION.
Virginia Saurman1, Korey Stevanovic1, Narek Israelyan1, Zi Shan Li2, Michael Gershon2, Isaac Snyder1, Kara G. Margolis1. 1Pediatrics, Columbia University Medical Center, New York, NY, USA; 2Pathology, Columbia University Medical Center, New York, NY, USA.

Gerald Odell Prize
HUMAN INDUCED PLURIPOTENT STEM CELL-DERIVED EXTRACELLULAR VESICLES REVERSE HEPATIC STELLATE CELL ACTIVATION.
Davide Povero1, Nidhi Goyal1, Lucas de Araujo Horcel1,2, Akiko Eguchi1, Paulina Ordonez1, Ariel E. Feldstein1. 1University of California San Diego, La Jolla, CA, USA; 2Centro Universitario Lusiada, São Paulo, Brazil.

KEYNOTE ADDRESS: PERSPECTIVES FROM NIDDK RELATED TO NASPGHAN
Griffin P. Rodgers MD, MACP, Director, National Institute of Diabetes and Digestive and Kidney Disease

CONCURRENT SESSION 3 - ENDOSCOPY II

EMBRYOLOGY MEETS ENDOSCOPY: THE ROLE OF ENDOSCOPY IN CONGENITAL GASTROINTESTINAL MALFORMATIONS
Michael Manfredi MD, Children’s Hospital Boston

PEDIATRIC ERCP IN THE SETTING OF ACUTE PANCREATITIS: A REPORT FROM THE MULTICENTER PEDIATRIC ERCP DATABASE INITIATIVE.
David M. Troendle1,2, Quin Y. Liu3,4, Kyung Mo Kim6,5, Doug Fishman7,8, Matthew Giefer10,9, Michael Wilsey11, Racha Khalaf11, Bradley A. Barth1,2. 1Pediatrics, UT Southwestern, Dallas, TX, USA; 2Children's Health, Children's Medical Center, Dallas, TX, USA; 3University of Southern California, Los Angeles, CA, USA; 4Children's Hospital of Los Angeles, Los Angeles, CA, USA; 5Asan Medical Center Children's Hospital, Seoul, Korea (the Republic of); 6University of Ulsan College of Medicine, Seoul, Korea (the Republic of); 7Baylor College of Medicine, Houston, TX, USA; 8Texas Children's Hospital, Houston, TX, USA; 9Seattle Children's Hospital, Seattle, TX, USA; 10University of Washington, Seattle, WA, USA; 11All Children's Hospital Johns Hopkins Medicine, St. Petersburg, FL, USA.

STATE OF THE ART RESEARCH LECTURE - BUILDING A CAREER IN PEDIATRIC ENDOSCOPY RESEARCH
Petar Mamula MD, Children’s Hospital of Philadelphia

FACTORS ASSOCIATED WITH INADEQUATE BOWEL PREPARATION FOR COLONOSCOPY IN CHILDREN - A PROSPECTIVE STUDY.
Sanjay Kumar, Courtney D. Gingerich, Emily Ferrell, Sandeep K. Gupta. Pediatric Gastroenterology, Riley Hospital for Children - Indiana University Health, Indianapolis, IN, USA.

CONCURRENT SESSION 3 - LIVER I

THREE DIMENSIONAL PRINTING OF HUMAN LIVER FOR SURGICAL PLANNING AND BEYOND
Nizar Zein MD, The Cleveland Clinic

SURVIVAL OUTCOME SCORES (SOFT, BAR AND PEDI-SOFT) ARE ACCURATE IN PREDICTING POST-LIVER TRANSPLANT SURVIVAL IN ADOLESCENTS.
Praveen Kumar Conjeevaram Selvakumar3, Brian Maksimak3, Ibrahim Hanouneh1, Dalia H. Youssef3, Rocio Lopez2, Naim Alkhouri3. 1Gastroenterology and Hepatology, Cleveland Clinic, Cleveland, OH, USA; 2Biostatistics, Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH, USA; 3Pediatric Gastroenterology, Cleveland Clinic, Cleveland, OH, USA.

MECHANISMS OF HEPATIC STEATOSIS: DIAGNOSTIC AND THERAPEUTIC IMPLICATIONS
Ariel Feldstein MD, University of California, San Diego

MIXED LINEAGE KINASE 3 MEDIATES RELEASE OF C-X-C MOTIF CHEMOKINE 10-BEARING EXTRACELLULAR VESICLES FROM LIPOTOXIC HEPATOCYTES.
Samar H. Ibrahim1, Petra Hirsova2, Steven F. Bronk2, Nathan W. Werneberg2, Stephen A. Harrison3, Harmeet Malhi2, Gregory J. Gores2. 1Pediatric Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; 2Gastroenterology and Hepatology, Mayo Clinic, Rochester, MN, USA; 3Gastoenterology and Hepatology, Brooke Army Medical Center, Fort Sam Houston, TX, USA.

CONCURRENT SESSION 3 – INFLAMMATORY BOWEL DISEASE II

DEBATE: HEAL THE MUCOSA OR HEAL THE PATIENT?
Cary Sauer MD, Emory Children’s Center vs. Shehzad Saeed MD, Cincinnati Children’s Hospital Medical Center

NASPGHAN Foundation/Crohn’s and Colitis Foundation Young Investigator Development Award
A METAGENOMIC APPROACH TO DIAGNOSIS, INDUCTION AND MAINTENANCE OF DEEP REMISSION FOLLOWING EXCLUSIVE ENTERAL NUTRITION IN PEDIATRIC CROHN’S DISEASE
Johann Van Limbergen MD, MRCPCH, PhD, IWK Health Centre

STATE OF THE ART RESEARCH LECTURE - STATURAL GROWTH IMPAIRMENT IN PEDIATRIC CROHN’S DISEASE
Neera Gupta MD, MAS Weill Cornell Medical Center

NASPGHAN Foundation Fellow to Faculty Transition Award in IBD
OXIDATIVE STRESS AND THE GUT MICROBIOME IN IBD TRANSITION
Lindsey Albenberg MD, Children’s Hospital of Philadelphia

CONCURRENT SESSION 3 – PRACTICE ECONOMICS 

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UPDATE ON CPT CODES AND ALTERNATIVE PAYMENT MECHANISMS
Joel Brill, MD, FAIR Health, Inc.

PRACTICE ECONOMICS: MISSION, MONEY, MIDAS AND MAGIC
David A. Piccoli MD, Children’s Hospital of Philadelphia

NASPGHAN WORKFORCE SURVEY RESULTS: HOW DO WE ALL STACK UP?
Linda Muir MD, FAAP, Oregon Health Science University

CONCURRENT SESSION 3 – FDA SESSION II – AN APPROACH TO ENDPOINT SELECTION IN CLINICAL TRIALS

REGULATORY CONSIDERATIONS IN SELECTING AN ENDPOINT
Preeti Venkataraman MD, Food and Drug Administration

EUROPEAN MEDICINES AGENCY (EMA) PERSPECTIVE ON THE DEVELOPMENT OF NEW MEDICINES IN GASTROENTEROLOGY
Richard Veselý MD, European Medicines Agency, London, UK

CLINICALLY MEANINGFUL ENDPOINTS IN EoE
Glenn Furuta MD, Children’s Hospital Colorado

CONCURRENT SESSION 3 – NUTRITION (Joint NASPGHAN/CPNP Session)

NUTRITIONAL ISSUES IN CHOLESTATIC DISEASE
Binita Kamath MBBChir MRCP MTR, The Hospital for Sick Children

NUTRITIONAL CHALLENGES IN CHILDREN WITH AUTISM
Cade M. Nylund, MD, MS, F. Edward Hébert School of Medicine Uniformed Services University

IRON DEFICIENCY AND THE DEVELOPING BRAIN
Michael Georgieff MD, University of Minnesota

CONCURRENT SESSION 4 - MALABSORPTION II

“ISLET” THEM TAKE MY WHOLE PANCREAS!
Jaimie Nathan MD, Cincinnati Children’s Hospital Medical Center

EARLY ENTERAL NUTRITION AND AGRESSIVE FLUID RESUSCITATION ARE ASSOCIATED WITH IMPROVED CLINICAL OUTCOMES IN ACUTE PANCREATITIS.
Flora K. Szabo, Lin Fei, Ligia M. Alfaro Cruz, Maisam Abu-El-Haija. Cincinnati Children's Hospital, Cincinnati, OH, USA.

STATE OF THE ART RESEARCH LECTURE - SOLVING A PEDIATRIC DILEMMA: DRUG-INDUCED PANCREATITIS
Sohail Husain MD, Children's Hospital of Pittsburgh of UPMC & the University of Pittsburgh

NASPGHAN Pancreas Prize –Supported by a grant from JOLI Diagnostic
TARGETING PANCREATIC CALCINEURIN TO PREVENT POST-ERCP PANCREATITIS.
Abrahim I. Orabi, Tanveer A. Javed, Swati Sah, John F. Eisses, Shunqian Jin, Sohail Z. Husain. Pediatric Gastroenterology, University of Pittsburgh, Pittsburgh, PA, USA.

CONCURRENT SESSION 4 – GUT MICROBIOME

RECENT ADVANCES IN FECAL MICROBIOTA TRANSPLANT
David Suskind MD, Seattle Children’s Hospital

STOOL BILE ACID PROFILES IN PEDIATRIC PATIENTS WHO RECEIVED FMT FOR CLOSTRIDIUM DIFFICILE INFECTION.
Mary Elizabeth M. Tessier1, Faith D. Ihekweazu1, Dorottya Nagy-Szakal1, Jonathan Crews2, Cana Ross3, Numan Oezguen3, Hoonmo Koo4, Michael Wang1, Ruth A. Luna3, James Versalovic3, Richard Kellermayer1, Tor Savidge1,3. 1Pediatric Gastroenterology, Baylor College of Medicine/ Texas Children's Hospital, Houston, TX, USA; 2Pediatrics- Infectious Disease, Baylor College of Medicine/ Children's Hospital of San Antonio, San Antonio, TX, USA; 3Pathology, Baylor College of Medicine, Houston, TX, USA; 4Medicine- Infectious Disease, Baylor College of Medicine, Houston, TX, USA.

STATE OF THE ART RESEARCH LECTURE – THE PEDIATRIC GUT MICROBIOME: THE FORGOTTEN ORGAN
Sonia Michail MD, Children’s Hospital of Los Angeles

IMPACT OF TREATMENT ON THE ESOPHAGEAL MICROBIOTA AND BACTERIAL RECEPTOR EXPRESSION IN EOSINOPHILIC ESOPHAGITIS.
Sophie A. Fillon1, Jonathan K. Harris2, Lauren Henry1, Ha Na Choe1, Brandie Wagner2, Wendy Moore1, Katie Amsden3, Amir F. Kagalwalla3, Angelika Zalewski4, Ikuo Hirano4, Nirmala Gonsalves4, Kathryn A. Biette1, Joanne C. Masterson1, Steven J. Ackerman5, Glenn Furuta1. Pediatrics Gastroenterology, University of Colorado Denver, Aurora, CO, USA; 2Pediatrics, University of Colorado Denver, Aurora, CO, USA; 3Pediatrics, Northwestern University Chicago, Chicago, IL, USA; 4Gastroenterology and Hepatology, Northwestern University, Chicago, IL, USA; 5Biochemistry and Molecular Genetics, University of Illinois at Chicago, Chicago, IL, USA.

CONCURRENT SESSION 4 - NEUROGASTROENTEROLOGY AND MOTILITY II

BRAIN-GUT INTERACTIONS: IMPLICATIONS IN NEUROGASTROENTEROLOGY
Kara Gross Margolis MD, Columbia University

NASPGHAN Motility Prize – Basic Science –Supported by a grant from MMS
IBUPROFEN SLOWS MIGRATION OF ENTERIC NERVOUS SYSTEM PRECURSOR CELLS INCREASING THE RISK OF HIRSCHSPRUNG-LIKE DISEASE IN ANIMAL MODELS.
Ellen M. Schill1,2, Jonathan I. Lake2, Olga Tusheva2, Nandor Nagy4,5, Saya K. Bery1, Lynne Foster6, Marina Avetisyan2, Stephen L. Johnson3, William F. Stenson6, Allan M. Goldstein4, Robert O. Heuckeroth1. 1Pediatrics, The Children's Hospital of Philadelphia and The Perelman School of Medicine at the University of Pennsylvania, Philadelphia, PA, USA; 2Pediatrics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; 3Genetics, Washington University School of Medicine in St. Louis, St. Louis, MO, USA; 4Pediatric Surgery, Massachusetts General Hospital, Harvard Medical School, Boston, MA, USA; 5Department of Human Morphology and Developmental Biology, Faculty of Medicine, Semmelweis University, Budapest, Hungary; 6Internal Medicine, Washington University School of Medicine in St. Louis, St. Louis, MO, USA.

THE OVERLAP BETWEEN INFLAMMATORY BOWEL DISEASE AND FUNCTIONAL GASTROINTESTINAL DISORDERS: CHALLENGES AND TREATMENT IMPLICATIONS
Miguel Saps MD, Nationwide Children’s Hospital

NASPGHAN Motility Prize – Clinical Science – Supported by a grant from MMS
PARENT-ONLY INTERVENTION REDUCES SYMPTOMS AND DISABILITY IN ABDOMINAL PAIN PATIENTS.
Rona L. Levy1, Miranda Van Tilburg2, Shelby L. Langer1, Joan M. Romano3, Lloyd A. Mancl4, William E. Whitehead2, Shara A. Feld5, Lynn S. Walker6. 1School of Social Work, University of Washington, Seattle, WA, USA; 2Medicine, University of North Carolina, Chapel Hill, NC, USA; 3Psychiatry and Behavioral Sciences, University of Washington, Seattle, WA, USA; 4Oral Health Sciences, University of Washington, Seattle, WA, USA; 5School of Medicine and Public Health, University of Wisconsin-Madison, Madison, WI, USA; 6Pediatrics, Vanderbilt University, Nashville, TN, USA.

CONCURRENT SESSION 4 – HOT TOPICS IN GI/LIVER: WHEN TO STOP…

IBD: IF MY PATIENT IS WELL ON COMBINATION THERAPY WHAT SHOULD I DO? BE HAPPY OR DE-ESCALATE THERAPY?
Andrew Grossman MD, Children’s Hospital of Philadelphia

LIVER TRANSPLANT AND IMMUNOSUPPRESSION: LESS OR NONE,SAFE OR SORRY?
Sandy Feng MD, PhD, University of California, San Francisco

SHOULD I TREAT EOSINOPHILIC ESOPHAGITIS AS A CHRONIC DISEASE?
Glenn Furuta MD, Children’s Hospital Colorado

CONCURRENT SESSION 4 – PSYCHOLOGY I - PSYCHOLOGICALLY-MINDED CARE IN PEDIATRIC GASTROENTEROLOGY CONDITIONS

PSYCHOSOCIAL ASPECTS OF CHRONIC GASTROENTEROLOGICAL ILLNESS
Bonnie Reed-Knight PhD, Emory University School of Medicine

WHAT HAPPENS BEHIND CLOSED DOORS: THE INS AND OUTS OF PSYCHOLOGICALTREATMENTS
Katherine Lamparyk Pys.D, Cleveland Clinic Children’s

PSYCHOLOGY AND GASTROENTEROLOGY: KEYS TO EFFECTIVE INTEGRATION
Anthony Alioto PhD, BCB, Nationwide Children’s Hospital

CONCURRENT SESSION 5 - IBD III

IMPROVE CARE NOW: EXPANDING ON A DECADE OF LEARNING
Wallace Crandall MD, Nationwide Children’s Hospital

GENETIC VARIATION IN VERY EARLY ONSET INFLAMMATORY BOWEL DISEASE.
Christopher J. Moran1, Judith Kelsen2, Jess L. Kaplan1, Hailiang Huang8, Manuel Rivas8, Noor Dawany9, Melvin B. Heyman3, Barbara Kirschner4, Thomas Mangatu4, Keith Benkov6, Jonathan E. Teitelbaum7, Stan Cohen12, Benjamin D. Gold12, Marcella Devoto10, Ramnik Xavier11, Robert Baldassano2, Mark J. Daly5, Harland S. Winter1. 1Pediatric Gastroenterology, MassGeneral Hospital for Children, Boston, MA, USA; 2Pediatric Gastroenterology, Children's Hospital of Philadelphia, Philadelphia, PA, USA; 3Pediatric Gastroenterology, University of California, San Francisco, San Francisco, CA, USA; 4Pediatric Gastroenterology, The University of Chicago Medicine Comer Children's Hospital, Chicago, IL, USA; 5Analytical and Translational Genetics Unit, Massachusetts General Hospital, Boston, MA, USA; 6Pediatric Gastroenterology, The Mount Sinai Hospital, New York, NY, USA; 7Pediatric Gastroenterology, Monmouth Medical Center, Long Branch, NJ, USA; 8Broad Institute, Cambridge, MA, USA; 9Department of Biomedical and Health Informatics, Children's Hospital of Philadelphia, Philadelphia, PA, USA; 10Division of Human Genetics, Children's Hospital of Philadelphia, Philadelphia, PA, USA; 11Gastroenterology, Massachusetts General Hospital, Boston, MA, USA; 12Children's Center for Digestive Health Care, Atlanta, GA, USA.

HEALTH MAINTENANCE OF IBD (VACCINATION/SKIN)
Paul Rufo MD, Children’s Hospital Boston

NASPGHAN Foundation Fellow to Faculty Transition Award in IBD
CMV INFECTION IN INDIVIDUALS WITH NK CELL LICENSING GENOTYPE PREDISPOSESTO INFLAMMATORY BOWEL DISEASE
Susy Yusung MD, Children’s Hospital, Los Angeles

CONCURRENT SESSION 5 - LIVER II

LONG TERM MANAGEMENT OF THE POST PEDIATRIC LIVER TRANSPLANT PATIENT: SOMETHING FOR EVERYONE TO CARE ABOUT
Vicky Lee Ng MD, The Hospital for Sick Children

MICRORNA-181 PROMOTES GRAFT PROLONGATION BY PLASMACYTOID DENDRITIC CELLS BY INCREASING T REGULATORY CELLS AND DECREASING B CELLS AS REVEALED BY MASS CYTOMETRY (CYTOF).
Audrey H. Lau1, Matthew Vitalone2, Xiumei Qu2, Todd Shawler2, Olivia M. Martinez2, Carlos O. Esquivel2, Sheri M. Krams2. 1Pediatrics, Division of Gastroenterology, Hepatology, and Nutrition, LPCH/Stanford University, Stanford, CA, USA; 2Surgery, Stanford University, Stanford, CA, USA.

STATE OF THE ART RESEARCH LECTURE - UNIQUE ASPECTS OF NEONATAL IMMUNITY PROVIDE CLUES TO THE PATHOGENESIS OF BILIARY ATRESIA
Cara Mack MD, Children’s Hospital of Colorado

PROSPECTIVE ANALYSIS OF PRESENTING FEATURES OF NEONATAL CHOLESTASIS – LIMITATIONS IN PREDICTIVE MODELS OF BILIARY ATRESIA.
Benjamin Shneider1, John C. Magee2, Nanda Kerkar4, Jeffrey Moore5, Wen Ye5, Saul Karpen3, Peter Whitington6, Jorge Bezerra7, Paula Hertel1, Jean Molleston8, Kasper Wang9, Henry Lin10, Robert Squires11, Philip Rosenthal12, Vicky Ng13, Yumirle Turmelle14, Kathleen Schwarz15, Averell Sherker16, Ronald J. Sokol for ChiLDReN17. 1Pediatric Gastroenterology, Hepatology and Nutrition, Baylor College of Medicine, Houston, TX, USA; 2University of Michigan Medical School, Ann Arbor, MI, USA; 3Pediatric Gastroenterology, Hepatology and Nutrition, Emory University School of Medicine/Children's Healthcare of Atlanta, Atlanta, GA,USA; 4Division of Gastroenterology, Hepatology and Nutrition, Childrens' Hospital of Los Angeles, University of Southern California, Los Angeles, CA, USA; 5Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA; 6Pediatrics Division of Gastroenterology, Hepatology, and Nutrition,Ann and Robert H Lurie Children's Hospital of Chicago, Chicago, IL, USA; 7Division of Pediatric Gastroenterology, Hepatology and Nutrition, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA; 8Department of Pediatrics, Department of Pediatric Gastroenterology, Hepatology and Nutrition, Indiana University School of Medicine, Indianapolis, IN, USA; 9Division of Pediatric Surgery, Children's Hospital Los Angeles, Los Angeles, CA, USA; 10Children's Hospital of Philadelphia, Philadelphia, PA, USA; 11Children's Hospital of Pittsburgh, Pittsburgh, PA, USA; 12Division of Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, UCSF Benioff Children's Hospital, San Francisco, CA, USA; 13The Hospital for Sick Children, Toronto, ON, Canada; 14Washington University School of Medicine, Saint Louis, MO, USA; 15Johns Hopkins School of Medicine, Baltimore, MD, USA; 16Liver Diseases Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD, USA; 17Section of Pediatric Gastroenterology, Hepatology and Nutrition, Department of Pediatrics, University of Colorado School of Medicine, Aurora, CO, USA.

CONCURRENT SESSION 5 - UPPER GI TRACT II

NERD: A FOUR LETTER WORD?
Rachel Rosen MD, Boston Children’s Hospital

CLAUDIN-7 DYSREGULATION IN PEDIATRIC EOSINOPHILIC ESOPHAGITIS: A ROLE FOR TGF-β1 IN ESOPHAGEAL EPITHELIAL BARRIER DYSFUNCTION.
Shahan D. Fernando1, Kathryn A. Biette1, David A. Kitzenberg2, Louise E. Glover2, Sean P. Colgan2, Glenn Furuta1, Joanne C. Masterson1. 1Pediatrics, University of Colorado, Denver, CO, USA; 2Medicine, University of Colorado, Denver, CO, USA.

STATE OF THE ART RESEARCH LECTURE - MANIPULATING GUT BACTERIA TO PREVENT THE ONSET OF CELIAC DISEASE
Alessio Fasano MD, Massachusetts General Hospital for Children

NON-INVASIVE MONITORING OF INTESTINAL PERMEABILITY AND INFLAMMATION IN A PROSPECTIVE SEROLOGICAL DIAGNOSIS STUDY OF PEDIATRIC CELIAC DISEASE.
Seema Rajani1, Hien Q. Huynh1,2, Leanne Shirton2, Cheryl Kluthe2, Don Spady1, Connie Prosser5, Jon Meddings4, Gwendolyn Rempel3, Rabindranath Persad1,2, Justine Turner1,2. 1Pediatrics, University of Alberta, Edmonton, AB, Canada; 2Gastroenterology, Stollery Children's Hospital, Edmonton, AB, Canada; 3Nursing, University of Alberta, Edmonton, AB, Canada; 4Medicine, University of Calgary, Calgary, AB, Canada; 5Stollery Children's Hospital, Edmonton, AB, Canada.

CONCURRENT SESSION 5 - BIO-BEHAVIORAL ASPECTS OF AND TREATMENTS FOR SPECIFIC GI CONDITIONS

ABDOMINAL PAIN: INTEGRATING PSYCHOLOGICAL TREATMENTS INTO MEDICAL CARE
Miranda vanTilburg PhD, University of North Carolina

CONSTIPATION AND SOILING: INTEGRATED MODELS OF CARE
Rose Schroedl PhD, Nationwide Children's Hospital

INTERDISCIPLINARY INPATIENT APPROACHES TO WEANING TUBE DEPENDENT CHILDREN FROM ENTERAL FEEDING
Alan Silverman PhD, Medical College of Wisconsin

CONCURRENT SESSION 5 - ETHICS

WHEN IS INFORMED CONSENT REALLY INFORMED?
Jeannie Huang MD, University of California, San Diego

ETHICS AND ADVOCACY IN THE MODERN ERA OF PEDIATRIC LIVER TRANSPLANTATION IN THE UNITED STATES
Evelyn Hsu MD, Seattle Children's Hospital

THE ETHICS OF INVESTIGATIONAL AND COMPASSIONATE USES
Kevin Donovan MD, Georgetown School of Medicine