Endoscopy Challenge #1 - May '09


HSV esophagitis is rare in the immunocompetent host but has been described in literature1-3. In pediatric patients (<18 years old), a retrospective study revealed male predominance2. This condition is either a result of primary infection with HSV or reactivation of a latent infection2. Endoscopy is important in establishing the diagnosis but histopathology may not reveal viral inclusions. For this reason, viral culture or PCR for herpes simplex virus plays a significant role in diagnosis 1,2. Although it is self-limited in immunocompetent hosts, intravenous acyclovir may hasten resolution of symptoms 3 as seen in this case report.

  1. Charina Ramirez, MD, Childrens Medical Center Dallas, University of Texas Southwestern

  2. Bradley Barth, MD, Children's Medical Center Dallas, University of Texas Southwestern

  3. Diagnosis