Endoscopy Challenge #1 - May '09

Discussion

HSV esophagitis is rare in the immunocompetent host but has been described in literature1-3. In pediatric patients (<18 years old), a retrospective study revealed male predominance2. This condition is either a result of primary infection with HSV or reactivation of a latent infection2. Endoscopy is important in establishing the diagnosis but histopathology may not reveal viral inclusions. For this reason, viral culture or PCR for herpes simplex virus plays a significant role in diagnosis 1,2. Although it is self-limited in immunocompetent hosts, intravenous acyclovir may hasten resolution of symptoms 3 as seen in this case report.

Authors:
  1. Charina Ramirez, MD, Childrens Medical Center Dallas, University of Texas Southwestern

  2. Bradley Barth, MD, Children's Medical Center Dallas, University of Texas Southwestern



  3. Diagnosis

    References